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Pharmacokinetic differences due to race have not been studied prospectively. Similarly, no plasma clearance variations were observed between black and Caucasian patients undergoing orthopedic surgical procedure.
The pharmacokinetic properties of fondaparinux sodium aren't considerably affected by gender. In vivo metabolism of fondaparinux has not been investigated since the majority of the administered arixtra dose is eliminated unchanged in urine in individuals with regular kidney operate. Thrombocytopenia associated with a optimistic in vitro test for anti-platelet antibody in the presence of fondaparinux sodium.
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